overuse knee injury advise?

The first thing I look at with bilateral knee pain is my shoes. Running the high mileage you are I would think you'd be getting new shoes every 3 or 4 months.  Beyond that I have no advice.  I'm dealing with knee pain myself trying to pinpoint the cause.

right or wrong, this is what I would do:   (I sometimes get a little LCL pain- usually just overuse, and if I back off, it heals within days)

1.  back off running.  depending on pain severity, either completely or just reduce mileage/intensity.  As you're training for an ultra... definitely back off the intensity.

2.  foam roller the hell out of that IT band.  

3.  I haven't tried them yet- but... Hokas?

As for the ice and advil route- it really depends on the cause of the injury.  If it's due to rubbing - then perhaps reducing the inflammation will reduce the internal abrasion factors.  If it's a degradation of the tendon due to overuse- then you kinda' need inflammation to do its job.  Ligaments don't get much blood flow as it is- so reducing blood flow further may not be your best healing therapy.  depends.

If you need/want to keep training, I would suggest doing a walk/run interval to help minimize the pain some. The less you run, the less pain you might have. That way you can keep upping the miles, but safely. This is what I do with clients who have injuries, or who come to me with not enough time to ramp up for an event. This helps me ensure they will stay injury free, while I ramp up their miles. 

Good luck! 

Its probably IT band rather an an LCL issue.......LCL is kind of hard to injure.  A blow to the medial side f your knee.  Good advice above, Stretch rest, foam roll, make sure your shoes are OK drop to a run walk for a while